Comparative evaluation of bis monitor indicators and stress hormone levels the adequacy of anesthesia

Aim: The aim of our research is to study the role of monitoring BIS (bispectral index) and stress hormones in assessing the adequacy of general anesthesia for extensive surgical interventions for severe abdominal pathologies.

Material and Methods: The research was conducted on 92 patients who underwent severe and traumatic surgical operations due to various surgical pathologies of the abdominal cavity. Throughout the surgical procedure, the level of general anesthesia and consciousness was assessed using the BIS monitor, as well as other indicators and the state of miorelaxation based on the electromyographic (EMG) index of the frontal muscles.

Results: The research results were analyzed and evaluated in 3 stages: 1st – initial, preoperative; 2nd – the most traumatic, stressful moments of the operation, and finally – 30 minutes after the end of the operation.

Conclusion: Consequently, it is important to think that general anesthesia should be based on hemodynamic, metabolic data, BIS and EMG data as indicators of adequate anesthesia. Management of the adequacy of general anesthesia are based on hormonal indicators of a stressor, clinical assessment of ACTH, cortisol and other hormonal indications that may not be achieved at this particular time, i.e., during anesthesia, for the clinical evaluation of these hormones, cannot be considered acceptable due to delay.